Gene information
Official symbol XDH
Official full name xanthine dehydrogenase
Gene type protein-coding gene
Chromosome2p23.1
Alias symbolXOR|XO
Resources
Entrez Gene 7498
HGNC HGNC:12805
Ensembl ENSG00000158125
Vega OTTHUMG00000099385
UCSC uc002rnv.2
GO terms: 52 records
GO Description Category LogP Number of genes Detail
GO:0001933 negative regulation of protein phosphorylation GO Biological Processes -19.8214973 59 More
GO:0001936 regulation of endothelial cell proliferation GO Biological Processes -54.5504306 75 More
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process GO Biological Processes -5.45408545 14 More
GO:0007589 body fluid secretion GO Biological Processes -11.5155091 20 More
GO:0007595 lactation GO Biological Processes -4.29648227 9 More
GO:0008285 negative regulation of cell population proliferation GO Biological Processes -53.5569125 147 More
GO:0010563 negative regulation of phosphorus metabolic process GO Biological Processes -21.7837721 71 More
GO:0010950 positive regulation of endopeptidase activity GO Biological Processes -13.2452311 34 More
GO:0010952 positive regulation of peptidase activity GO Biological Processes -14.1524623 37 More
GO:0030162 regulation of proteolysis GO Biological Processes -41.2267045 73 More
GO:0030856 regulation of epithelial cell differentiation GO Biological Processes -15.4645914 35 More
GO:0030857 negative regulation of epithelial cell differentiation GO Biological Processes -6.09984616 12 More
GO:0030879 mammary gland development GO Biological Processes -8.79064244 23 More
GO:0031400 negative regulation of protein modification process GO Biological Processes -17.0986645 70 More
GO:0032872 regulation of stress-activated MAPK cascade GO Biological Processes -11.6818048 20 More
GO:0032874 positive regulation of stress-activated MAPK cascade GO Biological Processes -9.63549885 15 More
GO:0042326 negative regulation of phosphorylation GO Biological Processes -20.6187298 64 More
GO:0042803 protein homodimerization activity GO Molecular Functions -14.2815375 77 More
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO Biological Processes -11.0338596 16 More
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process GO Biological Processes -14.7594418 39 More
GO:0043408 regulation of MAPK cascade GO Biological Processes -57.2547066 142 More
GO:0043410 positive regulation of MAPK cascade GO Biological Processes -49.4744054 112 More
GO:0045596 negative regulation of cell differentiation GO Biological Processes -26.9785067 101 More
GO:0045601 regulation of endothelial cell differentiation GO Biological Processes -11.5275821 17 More
GO:0045862 positive regulation of proteolysis GO Biological Processes -17.3242033 33 More
GO:0045936 negative regulation of phosphate metabolic process GO Biological Processes -21.8424865 71 More
GO:0046903 secretion GO Biological Processes -18.5147167 70 More
GO:0048732 gland development GO Biological Processes -26.3979320 74 More
GO:0050660 flavin adenine dinucleotide binding GO Molecular Functions -1.96545001 9 More
GO:0050678 regulation of epithelial cell proliferation GO Biological Processes -51.9930445 102 More
GO:0050680 negative regulation of epithelial cell proliferation GO Biological Processes -26.5961536 48 More
GO:0050878 regulation of body fluid levels GO Biological Processes -57.9546976 69 More
GO:0051345 positive regulation of hydrolase activity GO Biological Processes -19.7369783 79 More
GO:0051896 regulation of protein kinase B signaling GO Biological Processes -30.5149255 55 More
GO:0051898 negative regulation of protein kinase B signaling GO Biological Processes -8.06132628 15 More
GO:0052547 regulation of peptidase activity GO Biological Processes -35.5643317 55 More
GO:0052548 regulation of endopeptidase activity GO Biological Processes -34.9486589 53 More
GO:0070302 regulation of stress-activated protein kinase signaling cascade GO Biological Processes -11.5600448 20 More
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade GO Biological Processes -9.54226030 15 More
GO:0080135 regulation of cellular response to stress GO Biological Processes -19.0128542 89 More
GO:0090287 regulation of cellular response to growth factor stimulus GO Biological Processes -21.1381780 60 More
GO:0090288 negative regulation of cellular response to growth factor stimulus GO Biological Processes -9.39414218 23 More
GO:1900746 regulation of vascular endothelial growth factor signaling pathway GO Biological Processes -8.31468142 11 More
GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway GO Biological Processes -4.51852976 6 More
GO:1901136 carbohydrate derivative catabolic process GO Biological Processes -3.37180259 9 More
GO:1902532 negative regulation of intracellular signal transduction GO Biological Processes -29.4927428 92 More
GO:1902547 regulation of cellular response to vascular endothelial growth factor stimulus GO Biological Processes -7.92453051 11 More
GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus GO Biological Processes -4.18483678 6 More
GO:2000116 regulation of cysteine-type endopeptidase activity GO Biological Processes -14.4496812 41 More
GO:2000377 regulation of reactive oxygen species metabolic process GO Biological Processes -19.1025541 38 More
GO:2000379 positive regulation of reactive oxygen species metabolic process GO Biological Processes -15.0445998 16 More
GO:2001056 positive regulation of cysteine-type endopeptidase activity GO Biological Processes -11.1582582 17 More
Drug-Gene interaction
view
Related drugs: 21 records
Drug name Interaction type Source PMID View
allopurinol inhibitor TdgClinicalTrialChemblInteractionsTENDPharmGKBTTD 1650788427798726184095261965405319584965193763615415686194366711175235224915143200296182004620412184468 view
allopurinol sodium inhibitor ChemblInteractions view
azithromycin NCI 14730107 view
benzodiazepine NCI 2904285 view
carvedilol NCI 15853634 view
clarithromycin NCI 14730107 view
curcumin TTD view
didanosine PharmGKB 23315321 view
erythromycin NCI 14730107 view
febuxostat inhibitor TdgClinicalTrialChemblInteractionsTENDPharmGKBTTD 277987261713281024915143 view
fentanyl NCI 9637647 view
hypoxanthine NCI 15632148 view
insulin NCI 17370312 view
misonidazole NCI 2799816 view
nitrofurantoin NCI 6297496 view
oxypurinol TdgClinicalTrialTTD 1621403416135657 view
papaverine NCI 11200484 view
quercetin DTCNCI 609940821474216 view
roxithromycin NCI 14730107 view
theophylline PharmGKB view
topiroxostat TTD 10592235 view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
xanthine dehydrogenase/oxidase proteomics myocardial infarction[diagnosis] myocardial infarction Raghuvanshi R et al. Indian J Clin Biochem. 2007
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